Tapazole is a medicinal drug, which is composed of active ingredient Methimazole. It is indicated for the treatment of hyperthyroidism or overactive thyroid. This medication is composed of a conventional tablet form in dosages of 5 mg and 10 mg. This drug is manufactured by the renowned pharmaceutical company, King Pharmaceuticals Inc.
Manufacturer: King Pharmaceuticals Inc
Active Ingredient: This medication has active ingredient Methimazole, which is a thioamide inhibitor of the enzyme thyroid peroxidase. This component has antithyroid activity. It acts by inhibiting the metabolism of iodide and the iodination of tyrosine residues in the thyroid hormone precursor thyroglobulin by TPO. It also prevents the synthesis of this drug is an antithyroid medication indicated in the therapy of hyperthyroidism and Graves’ disease.
Indications: This mentioned medication is sed to prevent the thyroid gland from making excessive thyroid hormone. This popular brand medicine Tapazole is approved for the treatment of hyperthyroidism or overactive thyroid. It can be used before thyroid surgery or radioactive iodine treatment.
Action Mechanism: The condition of Grave's disease is an autoimmune disease caused by antibodies that attach to receptors on thyroid hormone-producing cells in the thyroid gland. It triggers an overproduction of the thyroid hormone. An enzyme that produces thyroid hormones, i.e., thyroxine (T4) and triiodothyronine (T3), by combining iodine with a protein called thyroglobulin. Tapazole prevents iodine and peroxidase from their normal interactions with thyroglobulin to form T4 and T3. This process reduces thyroid hormone production. It also interferes with the conversion of T4 to T3. It ultimately reduces the activity of thyroid hormones.
Dosages: This drug is available in dosages as mentioned below:
- 5 mg: This medicine should be taken 3 times a day or every 8 hours as advised by the doctor
- 10 mg: It is to be consumed 3 times a day with or without food as mentioned in the prescription by the doctor
Note: This medicine is not recommended in pregnant or breastfeeding women, it may harm babies.