Active Ingredient: The main active component of this medication is Midodrine Hydrochloride. This active component a direct-acting prodrug and sympathomimetic agent that has antihypotensive properties. It is converted to its active metabolite, desglymidodrine by deglycination reaction. It works by binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This induces smooth muscle contraction and results in an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier.
Indications: This particular medication is indicated for certain people who have symptoms of low blood pressure when standing. This condition is also called orthostatic hypotension. Proamatine is indicated in people whose daily activities are severely affected by this health condition. This is known as a sympathomimetic or alpha receptor agonist that effects on the blood vessels to promote blood pressure.
Action Mechanism: This effective drug Proamatine works by constricting the blood vessels and increasing blood pressure. It treats low blood pressure that induces severe dizziness or a light-headed feeling, like passing out. This drug may not improve the ability to perform daily activities.
Dosages: This medication is effective for the treatment of high blood pressure. It is available in a dosage as mentioned below:
- 2.5 mg: This drug should be taken 3 times a day with the gap of 3 to 4 hours with or without food as directed by the doctor
Note: This medicine is recommended in people who have severely low blood pressure that affects their daily life.