Generic Motegrity


Manufacturer: Shire US pharmaceuticals

Motegrity is an effective medicine used in the treatment of gastrointestinal disorders. It can be used in the treatment of conditions such as constipation, irritable bowel syndrome, hemorrhoids, anal fissures, perianal abscesses, fistulas, and perianal infections. This medicine contains the main active component Prucalopride Succinate. It is manufactured by a leading pharmaceutical company, Shire US Manufacturing Inc. It is made available in dosages of 1 mg and 2 mg.

SKU: Shire US Motegrity Categories: ,

Available Options

Generic Motegrity - 1mg

Pack SizePrice/unitPriceQtyAdd to cart
30 pills$0.95$28.50
60 pills$0.92$55.29
90 pills$0.88$79.52
120 pills$0.86$103.74
180 pills$0.85$152.19
240 pills$0.81$193.80

Generic Motegrity - 2mg

Pack SizePrice/unitPriceQtyAdd to cart
30 pills$1.20$36.00
60 pills$1.16$69.84
90 pills$1.12$100.44
120 pills$1.09$131.04
180 pills$1.07$192.24
240 pills$1.02$244.80


Active Ingredient

The main active ingredient is a Prucalopride Succinate in this medication. This active medicine available as a white to almost white powder. It is highly soluble in acidic aqueous media and alkaline aqueous media. It is indicated to treat chronic idiopathic constipation in adult female people in whom laxatives failed to offer adequate relief contains the active ingredient prucalopride succinate. It works on the muscle wall of the gut that restores the normal functioning of the bowel.

This active component is used in medicines to treat chronic constipation. It improves how well the stomach and intestines move food through the bowels during digestion.


Prucalopride Succinate composed medicine belongs to a class of drugs known as a serotonin-4 (5-HT4) receptor agonist. It is used in the treatment of gastrointestinal disorders. Motegrity is a medicine approved for the treatment of a chronic idiopathic constipation Idiopathic means without a known cause.

You Should Not Use Motegrity If You Have:

  • A Blockage In Your Intestines
  • Perforation Of Your Intestines
  • Severe Constipation
  • Inflammatory Bowel Disease (Crohn’s Disease, Ulcerative Colitis)
  • Toxic Megacolon

Action Mechanism

Given medication treats chronic constipation. Motegrity is prescribed when other drugs used to treat constipation like laxatives have not provided relief. This medicine works by improving process of passing food through stomach and intestines and the bowels during digestion.


This serotonin-4 (5-HT4) receptor agonist medication is available in dosages as mentioned below:

  • 1 mg: This drug should be taken orally once a day with or without food as directed by the doctor
  • 2 mg: It is to be consumed once a day as prescribed by the doctor


This medicine is contraindicated in people who have a blockage in the intestines, Crohn’s disease, ulcerative colitis, or intestinal perforation.

Additional information


1mg, 2mg


30 pills, 60 pills, 90 pills, 120 pills, 180 pills, 240 pills


$1.20, $1.16, $1.12, $1.09, $1.07, $1.02


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