Description
Active Ingredient
The main active component is Rosuvastatin, which is a statin with antilipidemic and potential antineoplastic activities. It binds to and inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a precursor of cholesterol. This leads to a decrease in hepatic cholesterol levels and an increase in the uptake of LDL cholesterol. This main component exhibits pro-apoptotic, growth inhibitory, and pro-differentiation activities in a variety of tumor cell types.
Indications
Rosuvastatin-composed medicine Crestor is used along with a proper diet to help lower “bad” cholesterol and fats such as LDL, triglycerides and raise “good” cholesterol in the blood. This medicine belongs to a group of drugs known as “statins.” While treating with this medicine, eating a proper diet, other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking.
Action Mechanism
This high cholesterol-treating medicine works by inhibiting HMG-CoA reductase, an enzyme that produces cholesterol in the liver. It lowers blood total cholesterol as well as blood LDL cholesterol levels. LDL cholesterol is the “bad” type of cholesterol that increases the risk of coronary artery disease and heart attacks. Lowering LDL cholesterol levels slows the progression of coronary artery disease and may even reverse it. It also increases HDL cholesterol, the “good” type of cholesterol, and reduces triglycerides.
Dosages
This medication Crestor is available for oral consumption and in dosage as mentioned below:
- 5 mg: It is to be consumed with or without food as directed by the doctor, usually once a day
- 10 mg: This medicine shall be taken before or after food as prescribed by the doctor
- 20 mg: This medicine is to be administered once a day as advised by the doctor
- 40 mg: Take this tablet as advised by the doctor, usually once a day
Note
This medicine is not advisable for pregnant women, it might hurt the fetus.
FAQ’s
What is Crestor?
Crestor (rosuvastatin) belongs to a group of drugs called HMG CoA reductase inhibitors, or statins. It reduces levels of bad cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood while enhancing levels of good cholesterol (high-density lipoprotein, or HDL).
Who can use Crestor?
Crestor is safe for consumption by adults and children who are at least 8 years old to lower cholesterol and triglycerides (types of fat) in the blood and to slow the build-up of plaque (fatty deposits) in your blood vessels
What is Crestor used for?
Crestor is used to lower the risk of stroke, heart attack, and certain other heart complications in men 50 years and older and women 60 years and older who have risk factors for heart disease.
How should be Crestor Consumed?
Keep using this medicine as directed, even if you feel well. High cholesterol usually has no symptoms. Hence, take Crestor on a long-term basis as directed by the doctor.
What should be avoided while consuming Crestor?
Avoid consuming foods high in fat or cholesterol. Crestor shall not be as effective in lowering cholesterol if a proper cholesterol-lowering diet plan is followed.
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