Generic Antabuse

Description

Active Ingredient:

The main active ingredient in the mentioned medicine is Disulfiram. It is a proteasome inhibitor that is indicated for the treatment of alcoholism, with potential antineoplastic and chemosensitizing activities. It may also help to treat alcoholism by binding to and inhibiting acetaldehyde dehydrogenase It is an enzyme that oxidizes the ethanol metabolite acetaldehyde into acetic acid.

This inhibition of acetaldehyde dehydrogenase results in an accumulation of acetaldehyde and produces a variety of very unpleasant symptoms. It shows a strong ability to chelate metals and its antineoplastic activity, highly dependent upon binding to copper, a metal that selectively accumulates in cancer cells.

Indications: 

Antabuse contains an active ingredient, which is an aid in the management of selected chronic alcohol people who want to remain in a state of sobriety so that supportive and psychotherapeutic treatment. Given medicine does not cure alcoholism. It should be used with proper motivation and supportive therapy; it shows a substantive effect on the drinking pattern of the chronic alcoholic.

Action Mechanism:

The action mechanism of this medicine depends on the active ingredient, Disulfiram. The enzyme called alcohol dehydrogenase helps to convert alcohol into acetaldehyde in the body. Another enzyme acetaldehyde dehydrogenase converts acetaldehyde into acetic acid. This conversion prevents acetaldehyde dehydrogenase from converting acetaldehyde into acetic acid, which leads to a buildup of acetaldehyde levels in the blood.

Dosages: 

Given medicine, Antabuse is available in conventional tablet form for oral administration offered in dosage as mentioned below:

• 500 mg: This medicine should be taken with or without food, usually once daily in the morning or as directed by the doctor

Note: 

Tell the doctor about the medical history of diabetes, an underactive thyroid, brain disorders such as seizures, brain damage, kidney disease, liver disease, or drug abuse before taking this medicine.

FAQ’s

What is Antabuse?

Antabuse is used in certain people with chronic alcoholism. This medicine helps in keeping away from drinking because of the unpleasant side effects that will occur if you consume alcohol while taking Antabuse.

What are the uses for abuse?

Antabuse is used for treating alcoholism. It is used in combination with supportive care and psychotherapy.

How should Antabuse be consumed?

Take Antabuse exactly as directed by the doctor. Follow all directions on the prescription label. The doctor may occasionally alter the dose to make sure and provide the best results.

What happens if the dosage of Antabuse is missed?

Take the missed dose as soon as you remember. Take the rest of the day’s doses at evenly spaced intervals unless directed by your doctor.

What other drugs shall affect Antabuse?

Seizure medications such as phenytoin (Dilantin) Blood thinning medications (including warfarin, Coumadin, Jantoven); Isoniazid.