Active Ingredient: Given medicine is composed of a combination of two active ingredients Quinapril Hydrochloride / Hydrochlorothiazide. Quinapril Hydrochloride is a non-sulfhydryl angiotensin-converting enzyme inhibitor that has antihypertensive activity. It binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. It also abolishes the potent vasoconstrictive actions of angiotensin II and results in vasodilatation. It causes a reduction in angiotensin II-induced aldosterone secretion by the adrenal cortex so as to promote the diuresis and natriuresis, and increases bradykinin levels.
Hydrochlorothiazide is a thiazide diuretic used to treat hypertension and edema. It appears to bind to and accumulate in red blood cells and excreted by the kidneys.
Indications: This mentioned medicine is indicated to treat high blood pressure. It acts by lowering high blood pressure that prevents strokes, heart attacks, and kidney problems. It is a combination of ACE inhibitors and diuretics. Accuretic works by relaxing blood vessels so blood can flow more easily and causing to produce more urine. This helps the body get rid of extra salt and water.
Action Mechanism: The combination of two active ingredients quinapril and hydrochlorothiazide. It is approved for the treatment of high blood pressure. Quinapril is an angiotensin-converting enzyme inhibitor that works by decreasing blood pressure by relaxing blood vessels and decreasing the workload of the heart. Hydrochlorothiazide is a water pill that helps control blood pressure by getting rid of excess salt and water.
Dosages: This mentioned medicine is available in dosage as given below:
- 10mg/12.5mg: It is to be taken once a day in the morning with or without food as directed by the doctor
- 20mg/12.5mg: This drug should be taken once a day as prescribed by the doctor
Note: This medication is not recommended in people who have ever had angioedema, or unable to urinate.