Pharmacia & Upjohn is the global pharmaceutical company emerged after the merger of Sweden-based Pharmacia AB and the American company Upjohn in 1995.  It has its roots in the United States to 1886. The company has grown throughout the 19th century, eventually evolving into an innovative, international company.

The Searle and Hereth Co. was formed by a Gideon Daniel Searle, as an innovative company developing many outstanding products. These include the first bulk laxative, the first motion sickness drug, the first oral contraceptive, the first once-a-day calcium channel blocker to treat high blood pressure., and many other innovative products. The company discovered and introduced aspartame, a hugely successful sugar substitute.

In April 2000, Pharmacia & Upjohn formed a meagered with Monsanto and Searle creating Pharmacia, a dynamic new competitor in the pharmaceutical industry. The trusted company’s innovative medicines and other products saved the lives of many people and enhanced health. After the merger, Pharmacia continued Searle’s agreement with Pfizer to co-promote Celebrex, which was originally co-developed by Searle and Pfizer.