Active Ingredient: This medicine has an active component Quetiapine Fumarate. This is a dibenzothiazepine derivative that shows the antipsychotic property. This active component antagonizes serotonin activity mediated by 5-HT 1A and 5-HT2 receptors. It has a lower affinity that reversibly binds to dopamine D1 and D2 receptors in the mesolimbic and mesocortical areas of the brain that leads to a reduction of psychotic effects. It decreases hallucinations and delusions.
Indications: This medication is approved to treat certain mental/mood conditions like schizophrenia, bipolar disorder, sudden episodes of mania or depression related to bipolar disorder. Seroquel is known as an anti-psychotic drug that helps to restore the balance of certain natural substances in the brain.
It also decreases hallucinations and improves concentration. It may also improve mood, sleep, appetite, and energy level. It can prevent severe mood swings or reduce how often mood swings occur.
Action Mechanism: This medicine is thought to work in the brain to treat schizophrenia. Seroquel is also known as a second-generation antipsychotic or atypical antipsychotic that rebalances dopamine and serotonin to improve thinking, mood, and behavior.
Dosages: It is available in dosage as mentioned below:
- 25 mg: This tablet must be taken orally with or without food as directed by the doctor
- 50 mg: It is to be consumed once a day as prescribed by the doctor
- 100 mg: Take this tablet once a day as mentioned in the prescription by the doctor
- 200 mg: Consume this medicine one times in a day as directed by the doctor
- 300 mg: It should be administered once a day as prescribed by the doctor
Note: It is contraindicated in mechanical intestinal or urinary obstruction, and particular caution should be used in people with bronchial asthma.
What is Seroquel?
Seroquel is a medication known as an atypical antipsychotic that is used to treat symptoms of schizophrenia. The medication is also sometimes used to treat symptoms of bipolar disorder.
When did the U.S. Food and Drug Administration (FDA) approve the medication?
Seroquel was first approved by the FDA in 1997.
Can children take Seroquel?
Seroquel has been approved to treat schizophrenia in children ages 13 and older. However, teens taking atypical antipsychotics can be at higher risk for side effects such as weight gain and suicidal thoughts and behaviors. Talk to the child’s doctor about the risks of using the medication.
Are there any other medical conditions that would make someone ineligible for Seroquel therapy?
Talk to the doctor about other medical conditions before taking Seroquel, such as a prolonged QT interval, diabetes, dementia, seizures, cataracts, low white blood cell count, high cholesterol, high or low blood pressure, a history of heart attack or stroke, breast cancer, thyroid cancer, heart disease, or liver disease.
What is the typical starting dose that would be prescribed to someone taking Seroquel?
The FDA recommends a starting dosage of 25mg twice a day for the treatment of schizophrenia. The safety of doses above 800 mg per day has not been established. Dosage may differ for the extended-release version of the medication and for the treatment of bipolar disorder.