This medicine has a main active component Cilostazol, which is a quinolinone derivative and cellular phosphodiesterase inhibitor, more specifically for phosphodiesterase III. The metabolite appears to inhibit PDE III activity, to suppress cyclic adenosine monophosphate (cAMP) degradation. It increases cAMP in platelets and blood vessels, leading to the inhibition of platelet aggregation and vasodilation.
Cilostazol composed medicine Pletal is a vasodilator that relaxes the muscles in your blood vessels to help them dilate. It dilates arteries that supply blood to your legs. This medicine also improves circulation by keeping platelets in the blood from sticking together and clotting.
This given medicine is used to treat the symptoms of intermittent claudication. It causes reduced blood flow to the legs, leading to pain while walking. It also improves your ability to walk longer distances without pain.
The cilostazol-composed drug exerts its action by inhibiting phosphodiesterase activity and suppressing cAMP degradation. The inhibition of PDE3 allows for a rise in cAMP in platelets and blood vessels.
This medication Pletal is available for oral consumption and in dosage as mentioned below:
- 25 mg: It is to be consumed without food as directed by the doctor, usually twice daily, at least 30 minutes before or 2 hours after breakfast and dinner
- 100 mg: Take this medicine twice a day, at least minutes before the meal, exactly as directed by the doctor
This medicine is not recommended for pregnant women; it could harm a nursing baby.
What is Pletal?
Pletal is a vasodilator that works by relaxing the muscles in the blood vessels for helping them dilate (widen). This medicine dilates arteries that supply blood to the legs. This medicine also enhances circulation by keeping platelets in the blood from sticking together and clotting.
What is Pletal used for?
The drug is used for treating the symptoms of intermittent claudication. This condition causes reduced blood flow to the legs, leading to pain while walking. This medicine improves the ability to walk longer distances without pain.
How to consume Pletal?
Pletal is usually taken twice a day on an empty stomach, at least 30 minutes before or 2 hours after breakfast or dinner. Take the medicine at the same time each day.
How long dosage of Pletal is to be consumed?
It may take up to 12 weeks before the symptoms might improve. Keep using the medication as directed and tell the doctor if symptoms do not improve even after 4 weeks of treatment.
What is to be avoided while taking Pletal?
Grapefruit and grapefruit juice may interact with Pletal and lead to unwanted side effects. Discuss the use of grapefruit products with the doctor.