Pletal is an effective medication used in the treatment of symptoms of intermittent claudication. This medication contains active ingredient Cilostazol, which is a quinolinone derivative. This medicine has been manufactured by the trusted company, Otsuka Pharmaceutical. It is available in a conventional tablet form in dosages are 25 mg and 100 mg.
Manufacturer: Otsuka Pharmaceutical
Active Ingredient: This medicine has a main active component Cilostazol, which is a quinolinone derivative and cellular phosphodiesterase inhibitor, more specific for phosphodiesterase III. The metabolite appears to inhibit PDE III activity, to suppress cyclic adenosine monophosphate (cAMP) degradation. It increases in cAMP in platelets and blood vessels, leading to inhibition of platelet aggregation and vasodilation.
Indications: Cilostazol composed medicine Pletal is a vasodilator that relaxes the muscles in your blood vessels to help them dilate. It dilates arteries that supply blood to your legs. This medicine also improves circulation by keeping platelets in the blood from sticking together and clotting.
This given medicine is used to treat the symptoms of intermittent claudication. It causes reduced blood flow to the legs, leading to pain while walking. It also improves your ability to walk longer distances without pain.
Action Mechanism: Cilostazol composed drug exerts its action by inhibiting phosphodiesterase activity and suppressing cAMP degradation. The inhibition of PDE3 allows for a rise in cAMP in platelets and blood vessels.
Dosages: This medication Pletal is available for oral consumption and in dosage as mentioned below:
- 25 mg: It is to be consumed without food as directed by the doctor, usually twice daily, at least 30 minutes before or 2 hours after breakfast and dinner
- 100 mg: Take this medicine twice a day, at least minutes before the meal, exactly as directed by the doctor
Note: This medicine is not recommended to pregnant women; it could harm a nursing baby.