Orap is a medicinal drug used to treat uncontrolled movements. It reduces the activity of a natural substance in the brain. It contains the main active component Pimozide. It is manufactured by the leading pharmaceutical company, Teva Pharmaceuticals USA, Inc. This medication is made available in dosages like 2 mg and 4 mg for oral administration.
Manufacturer: Teva Pharmaceuticals USA, Inc.
Active Ingredient: Pimozide ingredient acts as the main active component of this medicine. It is a dopamine antagonist that has antipsychotic properties. It inhibits type 2 dopaminergic receptors in the central nervous system to decrease dopamine neurotransmission and reduce the occurrence of motor and vocal tics and delusions of parasitosis. This factor antagonizes alpha-adrenergic and 5-HT2 receptors. It is a member of the class of benzimidazoles that is, which in turn is substituted on the nitrogen by a 4,4-bis butyl group. It plays the role of an H1-receptor antagonist, a serotonergic antagonist, a first-generation antipsychotic, an antidyskinesia agent and a dopaminergic antagonist.
Indications: This given drug is indicated to decrease uncontrolled movements like motor tics or outbursts of words/sounds i.e. vocal tics caused by Tourette syndrome. Orap is an effective medication that works by reducing the activity of a natural substance like dopamine in the brain.
This medicine should not be used for mild symptoms and it should only be used if symptoms cause severe problems in everyday life.
Action Mechanism: Pimozide composed medication that works by reducing the activity of a natural substance like dopamine in the brain. Orap should not be used for mild symptoms.
Dosages: Given medicine is available in a dosage as mentioned below:
- 2 mg: It is an oral drug usually taken once a day at bedtime with or without food, as directed by the doctor
- 4 mg: It is to be administered orally once a day at bedtime exactly as mentioned in the prescription by the doctor
Note: It is not recommended for people with long QT syndrome, low blood levels of potassium or magnesium. It must not be used in pregnant or breastfeeding women.