Generic Cortef


Manufacturer: Pharmacia Upjohn

Cortef is a popular brand of medication used to treat conditions like arthritis, breathing problems, cancer, or allergies. This medication is composed of the active ingredient Hydrocortisone. It is manufactured by the leading pharmaceutical company, Pharmacia & Upjohn. This popular brand of medicine is composed of conventional tablets in dosages 5 mg and 20 mg.

SKU: Pharmacia & Upjohn Cortef Categories: ,

Available Options

Generic Cortef - 5mg

Pack SizePrice/unitPriceQtyAdd to cart
60 pills $0.40$24.00
90 pills $0.39$34.92
120 pills $0.37$44.64
180 pills $0.36$65.52
240 pills $0.36$85.44
300 pills $0.34$102.00

Generic Cortef - 20mg

Pack SizePrice/unitPriceQtyAdd to cart
60 pills $0.62$37.20
90 pills $0.60$54.13
120 pills $0.58$69.19
180 pills $0.56$101.56
240 pills $0.55$132.43
300 pills $0.53$158.10


Active Ingredient

The main active component in the given medicine is Hydrocortisone. It is a synthetic or semi synthetic analog of natural hydrocortisone hormone formed by the adrenal glands with primary glucocorticoid and minor mineral corticoid effects. It promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. It is used in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.


This given medication is a natural substance called corticosteroid hormone made by the adrenal gland. Cortef is used to treat conditions like arthritis, blood/hormone/immune system disorders, skin and eye conditions, breathing problems, cancer, and severe allergies. It lowers the immune system’s response to various diseases to reduce symptoms like pain, swelling and allergic-type reactions.

Hydrocortisone is also used to treat low hydrocortisone levels caused by diseases of the adrenal gland like Addison’s disease, adrenocortical insufficiency. Corticosteroids are needed in many ways for the body to function well. They are important for salt and water balance and keeping blood pressure normal.

Action Mechanism

This medicine belongs to a class of drugs called glucocorticoids or adrenocorticoids. This drug is a steroid hormone which blocks certain proteins in your body that works to decrease swelling and stop your immune system from reacting to different triggers. Cortef also affects how the body uses and stores carbohydrates, proteins, and fats and how the body balances water and electrolytes.


Given medicine is available in dosages are mentioned below:

  • 5 mg: This medication shall be taken with food or milk to prevent stomach upset, exactly as directed by the doctor
  • 20 mg: It is to be consumed with food or milk as recommended by the doctor


This medicine shall not be used if a person has a fungal infection anywhere in the body.


What is Cortef?

Cortef is a steroid medicine used for treating many conditions like allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, multiple sclerosis, or lung disorders.

How does Cortef work?

Cortef affects your immune system and is is often used for treating certain blood cell disorders like anemia (low red blood cells) or thrombocytopenia (low platelets).

What are the side effects of Cortef oral?

Hydrocortisone side effects depend on the dose, the duration and the frequency of administration. Long term, high doses of Cortef usually will produce predictable and potentially serious side effects.

Which drugs or supplements interact with Cortef?

By interfering with the patient’s immune response, hydrocortisone can impede the effectiveness of vaccinations. Cortef interfere with the tuberculin skin test and cause false negative results in patients with tuberculosis infection.

What should be avoided while taking Cortef?

Do not receive a “live” vaccine while using Cortef. The vaccine may not work as well and may not fully protect you from disease. These conditions can be serious or even fatal in people who are using steroid medication.

Additional information


5mg, 20mg


60 pills, 90 pills, 120 pills, 180 pills, 240 pills, 300 pills


$0.40, $0.39, $0.37, $0.36, $0.36, $0.34


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