Coreg is a medicine composed of Carvedilol as the main active ingredient. It is indicated for the treatment of high blood pressure. One of the growing pharmaceutical companies, GlaxoSmithKline LLC manufactures this medicine. This pill is available in dosages as 10 mg, 20 mg, and 40 mg.
Manufacturer: GlaxoSmithKline LLC
Active Ingredient: This medicine contains the main active ingredient Carvedilol, which is a unique antihypertensive medication. It shows activity against both alpha- and beta-adrenergic receptors. The active component is a member of the class of carbazoles that is an adrenergic antagonist with non-selective beta- and alpha-1 receptor blocking properties. It helps in the treatment of congestive heart failure. It also acts as a beta-adrenergic antagonist, an antihypertensive agent, an alpha-adrenergic antagonist, a vasodilator agent, and a cardiovascular drug.
Indications: This mentioned medication is approved for the treatment of high blood pressure and heart failure. It also treats a heart attack to improve the chance of survival if the heart is not pumping well. Reducing elevated blood pressure prevents strokes, heart attacks, and kidney problems.
This effective pill Coreg works by blocking the action of certain natural substances in the body, such as epinephrine, on the heart and blood vessels. This results in a lowering of the heart rate, blood pressure, and strain on the heart.
Action Mechanism: Given beta-blocker medication, Coreg works by blocking the receptors of the adrenergic nervous system. This is the system of nerves in which adrenalin is active. Nerves from the adrenergic system enter the heart that releases an adrenergic chemical i.e. norepinephrine that attaches to receptors on the heart's muscle. This stimulates the muscle to beat more rapidly and forcefully. Due to blocking the receptors, this pill reduces the heart's rate and force of contraction. It also reduces the work of the heart.
Dosages: It is made available in various dosages as mentioned below:
- 3.125 mg: Usually, this pill should be taken once a day in the morning with food as prescribed by the doctor
- 6.25 mg: Take this pill once in a day preferably in the morning with food, not against the prescription by the doctor
- 12.5 mg: It is to be administered once in a day in the morning with breakfast, exactly as advised by the doctor
- 25 mg: Consume this tablet with food in the morning, usually once a day as advised by the doctor
Note: It is advisable to avoid driving or other activities that require alertness while treating with this pill.