Dostinex drug is composed of Cabergoline as the main active ingredient. It is effective for the treatment of conditions like hyperprolactinemic disorders. One of the leading pharmaceutical companies, Pfizer Inc offers this medicine. Available in a dosage of 0.5. mg.
Manufacturer: Pfizer Inc
Active Ingredient: This medicine contains Cabergoline as the main active ingredient. It is an N-acylurea, in which the hydrogen attached to the piperidine nitrogen is substituted by an allyl group. This active component is a dopamine D2 receptor agonist that is used in the management of Parkinson's disease and hyperprolactinemia. It actively plays the role of a dopamine agonist, an antiparkinson drug and an antineoplastic agent.
Indications: This tablet is an effective solution to treat hyperprolactinemic disorders, either idiopathic or due to pituitary adenomas. The condition hyperprolactinemia is a high level of prolactin in the body. It happens when the pituitary gland makes extra prolactin that can be caused due to a hormone problem or by a tumor in the pituitary gland.
It leads to changes in a woman’s ovulation, menstrual cycle, and breast milk production. Whereas, in men, it can affect reproduction and cause sexual issues such as decreased sex drive and not being able to get or keep an erection. All these are treated with this medicine.
Action Mechanism: Active component Cabergoline in the medicine Dostinex stimulates a specific type of dopamine receptor D2 receptors in the anterior pituitary gland. This helps to prevent the production of the hormone prolactin. It decreased the use of bromocriptine for the treatment of hyperprolactinemias i.e. abnormally high levels of prolactin in the blood. It might be more effective than other medications that treat the same condition.
Dosages: This medication is composed as a conventional tablet form. Dostinex is available in a dosage as mentioned below:
- 0.5 mg: This conventional pill is to be taken with or without food, usually twice a week exactly as mentioned in the prescription by the doctor
Note: Tell the medical history of liver disease, high blood pressure, heart valve disease, abnormal scarring/thickening of the lining in the lungs/heart/behind the abdomen i.e. pulmonary/pericardial/retroperitoneal fibrosis before consuming this medication.