Mestinon is composed of an active component Pyridostigmine Bromide, which is an acetylcholinesterase inhibitor. It is indicated in the treatment of symptoms of myasthenia gravis. It is available in a conventional tablet form, which is manufactured by the growing pharmaceutical company. The available dosage is 60 mg.
Manufacturer: Bausch Health Americas, Inc.
Active Ingredient: Pyridostigmine Bromide is the main active component of this medicine. It is a quaternary ammonium carbamate derivative and an acetylcholinesterase inhibitor. This active component binds to acetylcholinesterase active sites in the peripheral nervous system to prevent the breakdown of acetylcholine. It results in an accumulation of acetylcholine at cholinergic synapses and offers the transmission of impulses across the neuromuscular junction.
This medication increases the contraction of bronchial, intestinal smooth muscle and the secretions of the exocrine glands. It causes paralysis of the skeletal muscles mediated through nicotinic receptors. It is used as a reversible blocking agent to prevent organophosphates to protect the nervous system from the effects of nerve agents.
Indications: Pyridostigmine composed medicine affects chemicals in the body, which are involved in the communication between nerve impulses and muscle movement. Mestinon is indicated to treat the symptoms of myasthenia gravis. It is also used to improve muscle strength in people with a certain muscle disease like myasthenia gravis. It prevents the breakdown of a certain natural substance such as acetylcholine in the body.
Action Mechanism: Acetylcholine is one of many neurotransmitters in the body. Neurotransmitters help cells communicate with each other. Depending on the organ that it acts upon, acetylcholine produces different effects. It is important to produce muscle contractions and movement. In people with myasthenia gravis, there is a decrease in the levels of acetylcholine. This drug Mestinon can be used to increase acetylcholine levels and improve muscle contraction or movement. This medication increases the concentration of acetylcholine at nerve junctions by inhibiting cholinesterase, the enzyme that destroys acetylcholine.
Dosages: This medicine is made available in a dosage as mentioned below:
- 60 mg: It should be taken orally with or without food exactly as mentioned in the prescription by the doctor
Note: This medication should not be used in people with bladder or bowel obstruction.