Active Ingredient: Mirabegron is the main active component that belongs to a group of drugs known as the beta-3 adrenergic receptor. It has muscle relaxing, neuroprotective and potential antineoplastic activities. This drug binds to and activates ADRB3 that leads to smooth muscle relaxation. It also restores sympathetic stimulation in mesenchymal stem cell niches, inhibits JAK2-mutated hematopoietic stem cell expansion and blocks the progression of myeloproliferative neoplasms.
Indications: This mentioned drug is an effective solution for the treatment of overactive bladder. This health condition is a problem with how the bladder stores urine that causes a sudden urge to urinate. This urge may be hard to control, and overactive bladder symptoms may include frequent urination, strong sudden urges to urinate, or involuntary loss of urine. Myrbetriq relaxes a certain bladder muscle that helps the bladder hold more urine and lowers symptoms of overactive bladder.
Action Mechanism: Given medication is a Beta-3 adrenergic receptor agonist that induces relaxation of the detrusor smooth muscle of the urinary bladder. This process leads to an increase in the bladder capacity to hold the urine.
Dosages: This medication Myrbetriq is available in extended-release tablet form for oral consumption. It is available in dosages as mentioned below:
- 25 mg: This drug should be taken once a day with or without food as advised by the doctor
- 50 mg: This extended-release tablet must be taken once a day before or after a meal as prescribed by the doctor
Note: This drug is not recommended in people with uncontrolled hypertension.