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Tamoxifen Citrate

[ Generic Medicines for Women Treatment ]

Tamoxifen Citrate is a medicinal drug, which an antineoplastic nonsteroidal selective estrogen receptor modulator. This active component inhibits the binding of estradiol to estrogen receptors, to prevent the receptor from binding to the estrogen-response element on DNA. This process leads to a reduction in DNA synthesis and cellular response to estrogen. Additionally, it up-regulates the production of transforming growth factor B, a factor that inhibits tumor cell growth, and down-regulates insulin-like growth factor 1, a factor that stimulates breast cancer cell growth.

Class of Drugs – Antiestrogens

Molecular Formula – C32H37NO8

Molecular Weight - 563.6 g/mol

Working: Given medication is used as the main active component that belongs to a class of drugs known as antiestrogens. Tamoxifen Citrate blocks the effects of the hormone estrogen in the body. This hormone may induce the growth of some types of breast tumors and blocks the growth of tumors that respond to estrogen.

Uses: This is an effective medication indicated for the treatment of breast cancer. Tamoxifen Citrate is also approved to reduce the chances of breast cancer in high-risk patients. It can block the growth of breast cancer by interfering with the effects of estrogen hormone in the breast tissue.

Popular Brands and Dosages: This active component is used in a popular brand medication as given below:

  • Nolvadex: 10 mg and 20 mg

This medication may increase the risk of liver problems that cause loss of appetite and yellowing of the skin or the whites of the eyes.