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Thioridazine Hydrochloride

[ Generic Medicines for Schizophrenia Treatment ]

Thioridazine Hydrochloride is a piperidine phenothiazine derivative and a dopamine antagonist with the antipsychotic property. It is used as an active component that binds to mesolimbic postsynaptic dopamine receptor D2. It is to decrease the dopamine activity results in a decreased psychotic effect, like hallucinations and delusions. This agent binds to serotonin 5-HT2 receptors, resulting in decreased serotonin activity. It has a role as a first-generation antipsychotic that contains thioridazine.

Class of Drugs – Phenothiazine Drugs

Molecular Formula – C21H27ClN2S2

Molecular Weight - 407 g/mol

Working: This is an active component, which is an antipsychotic medicine called a phenothiazine. It acts by changing the actions of chemicals in the brain. Thioridazine Hydrochloride treats schizophrenia. This medication is usually given after other antipsychotic medicines have been tried and has no effect.

Uses: This mentioned medication is approved for the treatment certain mental/mood disorders like schizophrenia. It helps to think more clearly, feel less nervous, and take part in everyday life. Thioridazine Hydrochloride can also help prevent suicide in people likely to harm themselves, reduce aggression, and the desire to hurt others. This drug decreases the negative thoughts and hallucinations.

Popular Brands and Dosages: This phenothiazine medicine is used in a popular brand medicine as given below:

  • Mellaril: 25 mg

This medication is not approved in psychotic conditions related to dementia. It may increase the risk of death in older adults with dementia-related conditions.