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Esomeprazole Magnesium

[ Generic Medicines for Peptic Ulcer Treatment ]

Esomeprazole Magnesium is a medication belongs to a group of drugs called Proton Pump Inhibitors. It is the magnesium salt of esomeprazole with gastric proton pump inhibitor activity. This active component is protonated and converted into the active achiral sulphenamide. It acts by inhibiting its activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. This medicine is available in the delayed-release tablet form.    

Class of Drugs – Proton Pump Inhibitors

Molecular Formula – C34H36MgN6O6S2

Molecular Weight - 713.1 g/mol

Working: Given medicine is composed as a delayed-release tablet that reduces the amount of acid the stomach produces. This active component Esomeprazole Magnesium works by restricting the proton pump in the stomach’s cells. Due to the blockage of the proton pump, the stomach produces less acid than before.

Uses: Given proton pump inhibitor medicine decreases the amount of acid produced in the stomach. Esomeprazole Magnesium is indicated for the treatment of symptoms of gastroesophageal reflux disease and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome.

It is an active component used to promote healing of erosive esophagitis i.e. damage to the esophagus caused by stomach acid. It may also be given to prevent gastric ulcer caused by infection with Helicobacter pylori, or by the use of nonsteroidal anti-inflammatory drugs (NSAIDs).

Popular Brands and Dosages: This component is used as the main active ingredient in popular brand medicines as given below:

  • Nexium: 20 mg and 40 mg
  • Protonix: 20 mg and 40 mg
  • Prilosec: 20 mg and 40 mg
  • Aciphex: 20 mg and 40 mg

This medication is not for immediate relief of heartburn symptoms. Consume this medication exactly as prescribed by the doctor.