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Pentosan Polysulfate Sodium

[ Generic Medicines for Overactive Bladder Treatment ]

Janssen Elmiron

Pentosan Polysulfate Sodium is a medicinal drug, which is a semisynthetic heparin. It may act as a buffer to control cell permeability by protecting irritating solutes from reaching cells coated with it. It also adheres to the urinary bladder wall, preventing irritants from entering bladder cells and the development or progression of interstitial cystitis as a complication of some chemotherapies. This active factor also exhibits anticoagulant and fibrinolytic properties. It is available in capsule form for oral consumption.

Class of Drugs – Blood thinner

Molecular Formula – C10H18O21S4

Molecular Weight - 602.5 g/mol

Working: This active component is used as the active component in medicines to treat pain/discomfort from a certain bladder disorder or interstitial cystitis. It may also work by producing a layer on the bladder wall and protecting it from harmful/irritating substances in the urine. Pentosan Polysulfate Sodium is also a weak blood thinner and therefore may maximize the risk of bruising/bleeding.

Uses: Tis particular medicine is indicated for the treatment of pain/discomfort from a certain bladder disorder like interstitial cystitis. This medication may form a layer on the bladder wall and helps to protect it from harmful substances in the urine. Pentosan Polysulfate Sodium is a blood thinner that increases the risk of bruising/bleeding such as bleeding from the nose/gums.

Popular Brands and Dosages: This blood thinner active component is used in a popular brand medicine as mentioned below:

  • Elmiron: 100 mg

Medical history of bleeding disorders like hemophilia, thrombocytopenia, blood vessel disorders like aneurysm, liver disease, spleen disorders, stomach/intestinal disorders should be discussed with the doctor.