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Mirabegron

[ Generic Medicines for Overactive Bladder Treatment ]

Mirabegron is an active component, which is a bioavailable agonist of the human beta-3 adrenergic receptor. It shows different activities such as muscle relaxing, neuroprotective and potential antineoplastic. It binds to and activates ADRB3 that leads to smooth muscle relaxation. It acts by restoring sympathetic stimulation in mesenchymal stem cell niches and inhibiting JAK2-mutated hematopoietic stem cell expansion. It also blocks the progression of myeloproliferative neoplasms.

Class of Drugs – Beta-3 adrenergic agonists

Molecular Formula – C2s1H24N4O2S

Molecular Weight - 396.5 g/mol

Working: This medication acts as an active ingredient that belongs to a class of drugs called beta-3 adrenergic agonists. Mirabegron drug works by relaxing the muscle that surrounds the bladder. It may increase the bladder’s ability to store urine. It decreases the symptoms of overactive bladder.

Uses: It is indicated for the treatment of overactive bladder. This condition is a problem with how the bladder stores urine that causes a sudden urge to urinate. The urge to urinate might be hard to control. Symptoms of this condition are frequent urination, strong sudden urges to urinate, or involuntary loss of urine. Mirabegron relaxes a certain bladder muscle, which helps the bladder hold more urine and minimizes symptoms of overactive bladder.

Popular Brands and Dosages: This active component is used in a popular brand medicine as mentioned below:

  • Myrbetriq: 25 mg and 50 mg

Discuss the medical history of bladder problems, high blood pressure, kidney problems, and liver problems with the doctor before consuming this medicine.