Description
Active Ingredient:
Orlistat is an active ingredient used in medication to effectively lose unwanted weight. This medication is a reversible active-site inhibitor of gastrointestinal lipases. It inhibits the activity and prevents dietary fat from being hydrolyzed and absorbed. This active component is an inhibitor of pancreatic and gastric lipase and a commonly used weight loss agent. It is a carboxylic ester lead from the formal condensation of the carboxy group of N-formyl-L-leucine. A pancreatic lipase inhibitor, which is used as an anti-obesity drug. It plays the role of an EC triacylglycerol lipase inhibitor, a bacterial metabolite, fatty acid synthase inhibitor, and an anti-obesity agent.
Indications
This given effective drug is indicated with a doctor-approved exercise, behavior change, and reduced-calorie diet program to lose weight. Xenical is approved for a certain overweight people, such as those who are obese or have weight-related medical problems. Consuming orlistat can also help protect from gaining back weight after losing it. It reduces health risks that come with obesity, such as heart disease, diabetes, high blood pressure, and a shorter life.
Action Mechanism
Orlistat composed weight-loss drug works by blocking the enzyme that breaks down fats in the diet. Undigested fat then passes out of the body in a bowel movement. Xenical does not block the absorption of calories from sugar and other non-fat foods, so it needs to restrict the total intake of calories.
Common Side Effects
- Abdominal pain
- Fat in stool
- Abdominal cramp
- Flatulence
- Soft stools
- Flatus with discharge
- Oily spotting
- Diarrhea
Dosages
This medicine is available in dosages as mentioned below:
- 120 mg: This drug should be administered as directed by the doctor, with liquid sometime during each meal that contains fat or within 1 hour after the meal, usually 3 times daily.
Interaction with other drugs
- Acarbose
- Acenocoumarol
- Benfotiamine
- Alfacalcidol
Note
This medication should not use this drug in people with a digestive disorder, problems absorbing food, gallbladder problems.
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