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Rizatriptan Benzoate

[ Generic Medicines for Migraine Treatment ]

Rizatriptan Benzoate is used as the main active component in the medication to treat migraine headache. This component is a member of the triptan class agents that shows anti-migraine property. It binds to and activates serotonin 1B receptors expressed in intracranial arteries, and to 5-HT 1D receptors present on peripheral trigeminal sensory nerve terminals in the meninges and central terminals in brain stem sensory nuclei. Receptor binding leads to constriction of cranial vessels and inhibition of nociceptive transmission so as to providing relief of migraine headaches. It may also relief migraine headaches due to inhibition of pro-inflammatory neuropeptide release. It is available in an orally disintegrating tablet form.

Class of Drugs – Triptans

Molecular Formula – C22H25N5O2

Molecular Weight - 391.5 g/mol

Working: This mentioned medicine by narrowing blood vessels in the brain, restricting pain signals from being sent to the brain. Rizatriptan Benzoate also blocks the release of certain natural substances that cause pain, nausea, and other symptoms of migraine. It does not prevent migraine attacks or reduce the number of headaches occur.

Uses: Given medicine is approved for the treatment of migraines. It relieves headache, pain, and other migraine symptoms such as nausea, vomiting, sensitivity to light or sound. Immediate treatment helps to return to normal routine and may decrease the need for other pain medications. Rizatriptan Benzoate belongs to a group of drugs called triptans. This drug affects a certain natural substance that causes narrowing of blood vessels in the brain. It may also relieve pain by affecting certain nerves present in the brain. It does not prevent future migraines or lessen how often anyone gets migraine attacks.

Popular Brands and Dosages: This active component is used in popular brand medicine is as follows:

  • Maxalt: 5 mg and 10 mg
  • Maxalt-MLT: 5 mg and 10 mg

Medicine composed of above active ingredient should not be used for more than 10 days.