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Granisetron

[ Generic Medicines for Men & Women Treatment ]

Granisetron is the derivative of indazole with antiemetic properties. It is an active component belongs to a class of drugs known as a selective serotonin receptor antagonist. It blocks the action of serotonin at 5-HT3 receptors that leads to the suppression of chemotherapy and radiotherapy that induced nausea and vomiting. This medication is an antiemetic used for the prevention of postsurgical or chemotherapy-induced nausea and vomiting. It can be used after the therapy of diarrhea-predominant irritable bowel syndrome. This type of drug is associated with a low rate of transient serum enzyme elevations during therapy.

Class of Drugs – Serotonin type 3 receptor antagonist

Molecular Formula – C18H24N4O

Molecular Weight - 312.4 g/mol

Working: This medication belongs to a class of drugs known as serotonin type 3 receptor antagonist. Granisetron is indicated for the prevention of nausea and vomiting due to cancer drug treatment i.e. chemotherapy and radiation therapy. This active agent shows its action mechanism by blocking one of the body's chemicals like serotonin that causes vomiting.

Uses: This medicine is indicated for the prevention of nausea and vomiting related to initial and repeat courses of emetogenic cancer therapy that includes high-dose cisplatin. Granisetron can prevent the same with radiation, including total body irradiation and fractionated abdominal radiation.

Popular Brands and Dosages: The popular as mentioned below used this active ingredient as the main component to prevent nausea and vomiting during chemotherapy:

  • Kytril: 1 mg

Seek the medical help immediately in case of serious side effects occur such as chest pain, fast/irregular heartbeat, severe dizziness, and fainting.