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Aprepitant

[ Generic Medicines for Men & Women Treatment ]

Aprepitant is a medicinal drug with a high-affinity substance P antagonist with antiemetic activity. Crossing the blood-brain barrier, aprepitant binds to the human substance P/neurokinin 1 receptor in the central nervous system to inhibit the receptor binding of endogenous substance P and substance P-induced emesis. This active component has little or no affinity for serotonin type 3, dopamine, and corticosteroid receptors. It is an antiemetic agent that is indicated to prevent postoperatively or cancer chemotherapy-related nausea and vomiting.

Class of Drugs – An Antiemetic Drug

Molecular Formula – C23H21F7N4O3

Molecular Weight - 534.4 g/mol

Working: This medication is indicated with other drugs to help prevent nausea and vomiting induces by cancer drug treatment. Aprepitant acts by blocking one of the natural substances in the body that causes vomiting.

Uses: Given medication is approved with other drugs to help prevent nausea and vomiting caused by cancer drug treatment or chemotherapy. Aprepitant used to block one of the natural substances present in the body that leads to vomiting. It will not treat nausea or vomiting that has already started.

Popular Brands and Dosages: This effective medicine used as the main active component in a popular brand medicine as mentioned below:

  • Emend Tri-Pack: 80 mg and 125 mg

This drug should not be consumed if consuming pimozide medicine. A serious drug interaction can occur when pimozide is used together with this medication.