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What exactly is Tofranil?

Tofranil is a tricyclic antidepressant and brand name of the drug imipramine. It works by restoring balance to chemicals in the brain that helps regulate mood. The medication has been approved for treating depression in adults and nocturnal enuresis in children 6 and older.

When did the U.S. Food and Drug Administration (FDA) approve the medication?

Tofranil was first approved by the FDA in 1984.

Can children take Tofranil?

Very small doses of Tofranil are sometimes prescribed for nocturnal enuresis (involuntary urination), but the effectiveness and safety of the medication for treating other conditions in children such as ADHD has not been established.

Are there potential interaction issues for people taking Tofranil and any other drugs?

Do not take Tofranil if have taken an MAO inhibitor in the past two weeks, as a dangerous interaction effect could occur.

Are there any other medical conditions that would make someone ineligible for Tofranil therapy?

Talk to the doctor in case of glaucoma, seizures, heart disease, diabetes, kidney problems, liver problems, or a history of other mental illness, suicidal thoughts, or substance use.