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What is Valtrex?

Valtrex is an oral antiviral drug which is active against the herpes viruses.

What are uses of Valtrex?

Valtrex is used to treat infections with Shingles (herpes zoster), Genital herpes (herpes simplex genitalis), and Cold sores (herpes labialis).

Which drugs or supplements interact with Valtrex?

Probenecid (Benemid) and cimetidine (Tagamet) may reduce the kidney's clearance of Valtrex, leading to higher concentrations in the blood. This may lead to side effects of Valtrex.

Is Valtrex safe to use during pregnancy or while breastfeeding?

Valtrex showed no effects on the fetus in animal studies; however, there has been no adequate evaluation of valacyclovir or (acyclovir) in pregnant women. The incidence of birth defects in women taking acyclovir is about the same as in the general population. Valtrex should only be used during pregnancy when the benefits to the mother outweigh risks to the fetus.

How does Valtrex work?

Valtrex belongs to a class of drugs called nucleoside analogs that mimic one of the building blocks of DNA. It stops the spread of herpes virus in the body by preventing the replication of viral DNA that is necessary for viruses to multiply.