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Rosuvastatin

[ Generic Medicines for High Cholesterol Treatment ]

IPR Crestor

Rosuvastatin is a statin with antilipidemic and potential antineoplastic activities. Rosuvastatin selectively and competitively binds to and inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a precursor of cholesterol. This leads to a decrease in hepatic cholesterol levels and increases in uptake of LDL cholesterol. In addition, rosuvastatin, like other statins, exhibits pro-apoptotic, growth inhibitory, and pro-differentiation activities in a variety of tumor cell types; these antineoplastic activities may be due, in part, to inhibition of the isoprenylation of Ras and Rho GTPases and related signaling cascades.

Class of Drugs – Statins

Molecular Formula – C22H28FN3O6S

Molecular Weight - 481.5 g/mol

Working: This medication belongs to a group of drugs known as statins. Rosuvastatin acts by blocking enzymes in the liver that make cholesterol. It also lowers the levels of LDL cholesterol. It raises levels of HDL cholesterol in the body.

Uses: This medication is used along with a proper diet to help lower bad cholesterol and fats like LDL, triglycerides and raise good cholesterol in the blood. Rosuvastatin is a statin drug that works by reducing the amount of cholesterol made by the liver. Reducing the level of bad cholesterol and triglycerides, raising good cholesterol minimizes the risk of heart disease and helps to prevent strokes and heart attacks.

In addition to consuming a proper diet like a low cholesterol/low-fat diet, other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Talk with your doctor for more details.

Popular Brands and Dosages: This medication is used as the main active component in a popular brand medicine as follows:

  • Crestor: 5 mg, 10 mg, 20 mg, and 40 mg

While treating with this medication it is recommended to follow the diet and workout plan that the doctor advises.