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Verapamil

[ Generic Medicines for High Blood Pressure Treatment ]

Pfizer Calan

Pfizer Calan SR

Verapamil is a phenylalkylamine calcium channel blocking agent. This is the main active component inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, inducing dilatation of the main coronary and systemic arteries and reducing myocardial contractility. It also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents.

Class of Drugs – Calcium channel blocker

Molecular Formula – C27H38N2O4

Molecular Weight - 454.6 g/mol

Working: This medication is a calcium channel blocker that works to relax the blood vessels and improve blood flow, which helps to lower blood pressure. Verapamil affects the amount of calcium found in the heart and muscle cells, which relaxes blood vessels, which can reduce the amount of work the heart has to do.

Uses: Given medication is indicated to treat high blood pressure. Decreasing high blood pressure helps prevent strokes, heart attacks, and kidney problems. Verapamil belongs to a group of drugs known as calcium channel blockers. It acts by relaxing blood vessels so blood can flow more easily.

It is also used to prevent chest pain and to increase the ability to exercise and decrease how often you may get angina attacks. It controls the heart rate if you have a fast/irregular heartbeat. It helps to lower the heart rate.

Popular Brands and Dosages: Given calcium channel blocker medication is used as the main active component in popular brand medicines as follows:

  • Calan: 40 mg and 80 mg
  • Calan SR: 120 mg and 240 mg

This medicine is not recommended in people with a serious heart condition such as sick sinus syndrome or AV block, severe heart failure, Wolff-Parkinson-White, Lown-Ganong-Levine syndrome, or slow heartbeats that have caused you to faint.