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Lisinopril-Hydrochlorothiazide

[ Generic Medicines for High Blood Pressure Treatment ]

Lisinopril / Hydrochlorothiazide medicine is a combination of two active ingredients, i.e. Lisinopril and Hydrochlorothiazide. Lisinopril is an angiotensin-converting enzyme inhibitor with antihypertensive activity. It is a synthetic peptide derivative binds to and inhibits ACE that restricts the conversion of angiotensin I to angiotensin II. It prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation.

Hydrochlorothiazide is a thiazide diuretic used to treat hypertension and edema. It appears to bind to and accumulate in red blood cells and primarily excreted by the kidneys. It can be used to treat congestive heart failure. It plays the role of a xenobiotic, an environmental contaminant, a diuretic, and an antihypertensive agent.

Class of Drugs – ACE inhibitors + Thiazide Diuretic

Molecular Formula – C21H31N3O5 + C7H8ClN3O4S2

Molecular Weight - 405.5 g/mol + 297.7 g/mol

Working: One of the ingredients in the medicine hydrochlorothiazide removes the excess salt and water from the body. It keeps the heart from working as hard to pump blood. This lowers the blood pressure. The second ingredient, Lisinopril relaxes the blood vessels in the body that reduces stress on the heart and lowers the blood pressure.

Uses: This given active medication Lisinopril / Hydrochlorothiazide is a combination of two ingredients as the main active components. This drug treats high blood pressure by lowering high blood pressure that helps prevent strokes, heart attacks, and kidney problems. This product contains

Popular Brands and Dosages: Lisinopril / Hydrochlorothiazide is used in popular brand drugs as given below:

  • Zestoretic: 10 mg + 12.5 mg

In the case of diabetes, this medicine may affect blood sugar. Check the blood sugar regularly as directed and consult the doctor. Follow the exercises, diet, and instruction advised by the doctor.