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Irbesartan

[ Generic Medicines for High Blood Pressure Treatment ]

Irbesartan is an active component, which is a nonpeptide angiotensin II antagonist with antihypertensive activity. This component selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. It stimulates aldosterone synthesis and secretion by adrenal cortex that reduces the excretion of sodium and increases the excretion of potassium. Angiotensin II also works as a vasoconstrictor in vascular smooth muscle. It is a biphenylyltetrazole that is an angiotensin II receptor antagonist used for the treatment of hypertension. It plays the role of an antihypertensive agent, an angiotensin receptor antagonist, an environmental contaminant and a xenobiotic.

Class of Drugs – Angiotensin receptor blockers

Molecular Formula – C25H28N6O

Molecular Weight - 428.5 g/mol

Working: This medication belongs to a group of drugs called angiotensin receptor blockers. Irbesartan acts by blocking the effect of a hormone called angiotensin. This makes the blood vessels relax more. It also allows the kidneys to get rid of extra water and salt. It helps lower the blood pressure, and helps improve kidney function.

Uses: Given drug is indicated to treat high blood pressure and to help protect the kidneys from damage due to diabetes. Decreasing high blood pressure helps prevent strokes, heart attacks, and kidney problems. Irbesartan is an angiotensin receptor blocker that works by relaxing blood vessels so that blood can flow more easily.

Popular Brands and Dosages: This mentioned medication is indicated as the active ingredient in a popular brand medicine as given below:

  • Avapro: 150 mg + 300 mg

This medication is not recommended for breastfeeding pregnant women. It may harm nursing infant or fetus.