Vaseretic is a medication contains active components Enalapril Maleate and Hydrochlorothiazide. It is used to treat hypertension and edema. It has been offered by leading pharmaceutical companies, Valeant Pharmaceuticals North America LLC. It is made available in dosages as 5 mg + 12.5 mg and 10 mg + 25 mg. It is composed of a conventional tablet for oral consumption.
Manufacturer: Valeant Pharmaceuticals North America LLC
Active Ingredient: Given effective medicine is composed of active ingredients i.e. Enalapril Maleate and Hydrochlorothiazide. Enalapril Maleate contains a peptide and angiotensin-converting enzyme inhibitor that shows antihypertensive activity. It is converted by de-esterification into its active form enalaprilat. It prevents the potent vasoconstrictive actions of angiotensin that results in vasodilation.
Hydrochlorothiazide is a thiazide diuretic used to treat hypertension and edema. It is also used in the treatment of hypertension and congestive heart failure. It plays the role of a xenobiotic, an environmental contaminant, a diuretic, and an antihypertensive agent.
Indications: This particular medicine Vaseretic is used in the treatment of high blood pressure. Reducing high blood pressure prevents strokes, heart attacks, and kidney problems. It contains 2 medications, enalapril, and hydrochlorothiazide i.e. ACE inhibitors and diuretic. It can also be used to relax the blood vessels so that blood can flow through the body more easily.
Action Mechanism: A combination of active ingredients used for treating high blood pressure. It belongs to a class of drugs called angiotensin-converting enzyme inhibitors. It causes contraction of the muscles surrounding the arteries in the body, so as to narrow the arteries and elevate the blood pressure. These drugs lower the blood pressure by preventing the formation of angiotensin II aiming at relaxing the arteries.
Vaseretic works by blocking salt and water reabsorption in the kidneys to increased urine output. The mechanism is lowering high blood pressure is known exactly.
Dosages: A combination of medicines is offered in dosages as given below:
- 5 mg + 12.5 mg: It is to be taken at least 4 hours before bedtime with a glass of water, as directed by the doctor
- 10 mg + 25 mg: Administer this drug exactly as mentioned in the prescription by the doctor, usually 4 hours before bedtime
Note: This medicine can make you sunlight sensitive. Advisable to use sunscreen and wear protective clothing when outdoors.