Amlodipine Besylate / Olmesartan Medoxomil
[ Generic Medicines for High Blood Pressure Treatment ]
Amlodipine Besylate / Olmesartan Medoxomil Is a combination of two active components used to treat high blood pressure. This medication is a synthetic dihydropyridine with antihypertensive and antianginal effects. It acts by inhibiting the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells to prevent the vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries decreased myocardial contractility, increased blood flow and oxygen delivery to the myocardial tissue, and decreased total peripheral resistance.
Olmesartan Medoxomil component shows an antihypertensive property. After hydrolysis, this ingredient is converted to Olmesartan that binds to the angiotensin type 1 (AT1) receptor of angiotensin II in vascular smooth muscle and adrenal gland to compete for angiotensin II binding to the receptor.
Class of Drugs – Angiotensin II receptor antagonist
Molecular Formula – C26H31ClN2O8S + C29H30N6O6
Molecular Weight - 567.1 g/mol + 558.6 g/mol
Working: Given medication acts by relaxing the muscles of the heart and blood vessels. Amlodipine Besylate / Olmesartan Medoxomil has a component belongs to a class of drugs called angiotensin II receptor antagonists and calcium channel blockers. This drug keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. It is used in the treatment of high blood pressure.
Uses: This medication is approved to treat high blood pressure i.e. hypertension. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It contains 2 medications: Amlodipine Besylate / Olmesartan Medoxomil both work by relaxing blood vessels so blood can flow more easily. Amlodipine is a calcium channel blocker and olmesartan is an angiotensin receptor blocker (ARB).
Popular Brands and Dosages: This medication is used as the active ingredient in a popular brand medicine as given below:
- Azor: 5 mg+ 20 mg and 5 mg + 40 mg
In case you are taking drugs to lower the cholesterol this medication should be taken at least 4 hours before any of these medications.