[ Generic Medicines for Fungal Treatment ]
Ketoconazole is a derivative of phenylpiperazine and used as the main active component in medications used to treat fungal infections. This drug shows broad antifungal properties and antineoplastic activity. This active agent works by inhibiting the sterol, a microsomal cytochrome dependent enzyme so as to disrupt the synthesis of ergosterol. It is an important factor in the fungal cell wall. This component is an imidazole fungicidal agent that acts against many fungal species so used for the treatment of superficial and systemic fungal infections. It is offered in conventional tablet form.
Class of Drugs – Azole-antifungals
Molecular Formula – C26H28Cl2N4O4
Molecular Weight - 531.4 g/mol
Working: This given antifungal agent Ketoconazole is indicated in the treatment of certain serious fungal infections in the body. This medication is an active component belongs to the class of drugs known as azole antifungals. The action mechanism of this medicine is by restricting and stopping further growth of the fungus.
Uses: Azole-antifungal medication is approved for the treatment of skin infections like athlete's foot, jock itch, ringworm, and certain kinds of dandruff. Ketoconazole treats a skin condition known as pityriasis i.e. tinea versicolor, a fungal infection, which causes a lightening or darkening of the skin of the neck, chest, arms, or legs. It acts by preventing the growth of fungus in the body.
Popular Brands and Dosages: This mentioned antifungal medication works as the main active component in a popular brand medicine as given below:
- Nizoral: 200 mg
Do not use any other antifungal medicine while treating with this medicine. It can cause serious harm to the liver that may result in liver transplant or cause death. This medicine is not recommended in the treatment of fungal infections of the fingernails or toenails. Do not use it in conditions like prostate cancer or Cushing syndrome.