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Griseofulvin

[ Generic Medicines for Fungal Treatment ]

Griseofulvin is a medication belongs to a class of drugs known as an antifungal agent that derived from the mold Penicillium Griseofulvin. It is indicated for the treatment of fungal infections of the skin and nails. It is an active ingredient that binds to tubulin, disrupting microtubule function and inhibiting mitosis. It is a Tubulin Inhibiting Agent that shows physiologic effect of griseofulvin by means of Decreased Mitosis, and Microtubule Inhibition. It is also called a fungistatic agent that treats superficial fungal skin infections like tinea capitis and pedis. It is available as conventional tablet form.

Class of Drugs – Anti-fungal drugs

Molecular Formula – C17H17ClO6

Molecular Weight - 352.8 g/mol

Working: This antifungal drug shows its action mechanism by binding to a part of the fungus causing the infection in the body. This process can obstruct the fungus from multiplying. The active agent Griseofulvin also prevents fungus from spreading to new cells that causes the infection to die off.

Uses: This mentioned active agent is used in the medicines to treat fungal infections of the skin, hair, and nails. It is to be used when the infections do not respond to creams/lotions. Expanse of such infections will get rid of symptoms for instance itching, red/peeling/scaly skin, and discolored nails. Given medicine acts by restricting the growth of fungi. This medicine should not be used to treat infections caused by bacteria or yeast.

Popular Brands and Dosages: Given antifungal medicine, Griseofulvin is used as the main active ingredient in a popular brand medicine as follows:

  • Grifulvin V: 500 mg

This medicine is an antifungal that works best when the amount of medicine in the body is kept at a constant level. It should be taken after equal intervals.