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Topiramate

[ Generic Medicines for Epilepsy Treatment ]

Topiramate is an active component used in medicines, which belongs to a group of drugs called anticonvulsants. This active component antagonizes the kainate/AMPA subtype of the glutamate receptors that are ligand-activated cation channels that mediate the fast component of excitatory postsynaptic in the central nervous system. This action leads to the stabilizing hyper-excited neural membranes that inhibit repetitive neuronal firing and decreases the propagation of synaptic impulses. It is to impede seizure occurrences.

Class of Drugs – Anticonvulsant

Molecular Formula – C12H21NO8S

Molecular Weight - 339.36 g/mol

Working: This anticonvulsant medication belongs to a class of drugs called sulfamate-substituted monosaccharide anticonvulsants or antiepileptic drugs. The exact mechanism of working of this drug is known completely. It is thought that Topiramate acts on certain chemicals, channels, receptors, and enzymes in the brain to help control seizures and prevent migraines.

Uses: This mentioned medication is indicated alone or with other drugs to prevent and control seizures or epilepsy. It can be used to prevent migraine headaches and reduce how often anyone gets them. Topiramate is not recommended for the treatment of a migraine headache once it occurs. If anyone gets a migraine headache, treat it as directed by the doctor.

Popular Brands and Dosages: This medicine belongs to a group of drugs known as anticonvulsants. It is used as an active ingredient in a popular brand drug as mentioned below:

  • Topamax: 25 mg, 50 mg, 100 mg, and 200 mg

This drug can increase body temperature and decrease sweating which may lead to life-threatening dehydration.