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Repaglinide

[ Generic Medicines for Diabetes Treatment ]

Repaglinide is an active ingredient belongs to a group of drugs called meglitinide. It shows hypoglycemic activity. This component rapidly absorbed and is metabolized in the liver by CYP2C8 and CYP3A4 and metabolites are excreted in the bile. This ingredient antihyperglycemic agent indicated for the treatment of non-insulin-dependent diabetes mellitus. This short-acting insulin secretagogue binds to cells of the pancreas to stimulate insulin release. It induces an early insulin response to meals reducing postprandial blood glucose levels.

Class of Drugs – Meglitinides

Molecular Formula – C27H36N2O4 s

Molecular Weight - 452.6 g/mol

Working: This active component works by inducing the pancreas to produce insulin. Repaglinide works by reducing glucose formation in the liver and reducing the absorption of glucose by the intestines. This ingredient should be taken with diet and exercise to treat type 2 diabetes. It may cause hypoglycemia although the risk is thought to be lower than that of sulfonylureas since their action is dependent on the presence of glucose.

Uses: This medication is indicated alone or with other medications to control high blood sugar along with a proper diet and exercise program. Repaglinide composed medicine is approved in people with type 2 diabetes. It acts by controlling high blood sugar that prevents kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may help to lower the risk of a heart attack or stroke. It stimulates the body to form more insulin, which is a natural substance that allows the body to properly use sugar from the diet.

Popular Brands and Dosages: This is an active component used in a popular brand medicine as given below:

  • Prandin: 0.5 mg and 1 mg

This medication should be taken regularly as directed by the doctor in order to get the most benefit from it.