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Lithium Carbonate

[ Generic Medicines for Depression Treatment ]

Lithium Carbonate is a medication with antimanic and hematopoietic activities. It interferes with transmembrane sodium exchange in nerve cells and affects sodium, potassium-stimulated adenosine triphosphatase. This medicine alters the release of neurotransmitters, affects cyclic adenosine monophosphate concentrations, and blocks inositol metabolism. It results in depletion of cellular inositol and inhibition of phospholipase C-mediated signal transduction. It acts by mood-stabilizing effect. It also stimulates granulocytopoiesis and increases the level of pluripotent hematopoietic stem cells by stimulating the release of hematopoietic cytokines or directly acting on hematopoietic stem cells.  It is available in the capsule form.

Class of Drugs – Hematopoietic Agent

Molecular Formula – Li2CO3

Molecular Weight - 73.9 g/mol

Working: This mentioned medicine obstructs with the formation and uptake of chemical messengers by which nerves communicate with each other i.e. neurotransmitters. Lithium Carbonate also affects the concentrations of tryptophan and serotonin in the brain. Additionally, the ingredient increases the production of white blood cells in the bone marrow. Its effects usually begin within 1 week of starting treatment.

Uses: It is approved for the treatment of manic-depressive disorder or bipolar disorder. It stabilizes the mood and reduces extremes in behavior by restoring the balance of certain natural substances like neurotransmitters in the brain. Lithium Carbonate decreases how often manic episodes occur and decreases the symptoms of manic episodes such as exaggerated feelings of well-being, feelings that others wish to harm, irritability, anxiousness, rapid/loud speech, and aggressive/hostile behaviors.

Popular Brands and Dosages: This effective active component is used in a popular brand medicine as mentioned below:

  • Eskalith: 300 mg

It is advisable to drink 8 to 12 glasses of water or other fluid each day, and eat a healthy diet with normal amounts of salt as directed by the doctor or dietician while treating with this medication.