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Isosorbide Mononitrate

[ Generic Medicines for Cardiac Treatment ]

Isosorbide Mononitrate medicine is an organic nitrate with an activity of vasodilator. This drug is an active ingredient that relaxes the vascular smooth muscle by the formation of nitric oxide. These are identical to the endothelium-derived relaxing factor. Nitrogen oxide activates guanylyl cyclase so as to increase the synthesis of cGMP within a smooth muscle that leads to dephosphorylation of light chain myosin. It also helps to relax the peripheral arteries and veins. This ingredient widens coronary arteries so as to increase the blood circulation through the ischemic area.

Class of Drugs – Nitrates

Molecular Formula – C6H9NO6

Molecular Weight - 191.14 g/mol

Working: Given medicine is used as the active component belongs to the group of medicines called nitrates. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. When used regularly on a long-term basis, this helps prevent angina attacks from occurring.

Uses: This active component is used to prevent chest pain like angina in people with a certain heart condition such as coronary artery disease. This nitrate medicine relaxes and widens blood vessels so blood can flow more easily to the heart. Isosorbide Mononitrate will not relieve chest pain once it occurs. This medication is not intended to be taken just before physical activities like exercise or sexual intercourse to prevent chest pain.

Popular Brands and Dosages: Given medication belongs to a group of drugs known as nitrates. It is used as the main active component in a popular drug as mentioned below:

  • Monoket: 20 mg, 30 mg, and 60 mg

Consumption of tobacco-containing products should be avoided while treating with this medicine. It may affect the effectiveness of this medicine.