Aggrenox is a popular medication used in the treatment of stroke prevention. It contains a combination of Dipyridamole - Acetylsalicylic Acid. It belongs to a group of drugs called salicylates. It reduces substances in the body that cause pain, fever, and inflammation. Dipyridamole keeps platelets in the blood from sticking together to form clots. It is used to reduce the risk of stroke in people who have had blood clots. Boehringer Ingelheim Pharma, one of the top pharmaceutical companies has been manufacturing this medicine. It is available in a conventional tablet form in a dosage of 200 mg + 25 mg.
Manufacturer: Boehringer Ingelheim Pharma
Active Ingredient: Given medicine is a combination of two active ingredients. Dipyridamole is a synthetic agent derivative of pyrimido-pyrimidine, with antiplatelet properties. It inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate. It inhibits the stimulation of platelet aggregation by agents such as platelet activating factor and collagen.
Aspirin is a non-steroidal antiinflammatory agent that binds to and acetylates serine residues in cyclooxygenases, resulting in decreased synthesis of prostaglandin, platelet aggregation, and inflammation.
Indications: Given medication is approved to reduce the risk of stroke in patients who have had "mini-strokes" or a previous stroke due to a blood clot and are at high risk for another stroke. This medicine composed of two components. It works to keep blood flowing to the brain by stopping platelets from clumping together. Aggrenox prevents the platelets from forming blood clots, which can lodge in the brain and cause a certain type of stroke (ischemic stroke).
Action Mechanism: This medicine a combination of is an aspirin/extended-release dipyridamole combination that acts on multiple mechanisms of the platelet-aggregation process to prevent clumping and clotting.
Dosages: This medication Aggrenox is available for oral consumption and in dosage as mentioned below:
- 200 mg + 25 mg: It is an oral drug shall be taken with or without food as directed by the doctor, usually twice a day
Note: You should not take this medicine if you have asthma and also have polyps in your nose.